What does the term 'buccal' refer to?

The term 'buccal' refers specifically to the cheek area in relation to the mouth. In medical and pharmacological contexts, buccal administration refers to the placement of medication between the gum and the inner lining of the cheek, allowing for absorption directly into the bloodstream through the mucous membranes. This method is beneficial for certain drugs because it bypasses the digestive system and first-pass metabolism in the liver, leading to a more rapid onset of action. This definition aligns with the correct answer, highlighting the anatomical significance of buccal administration in pharmacology.