What is the primary therapeutic use of Clonidine?

Clonidine is primarily used for the reduction of hypertension. It acts as an alpha-2 adrenergic agonist, which means it stimulates certain receptors in the brain that lead to a decrease in the release of norepinephrine. This results in reduced sympathetic outflow from the central nervous system, leading to vasodilation and a corresponding decrease in blood pressure.

While clonidine has effects that might contribute to the management of anxiety and can occasionally be used in certain contexts related to anxiety relief, its main indication in clinical practice remains the effective management of high blood pressure. Additionally, it does not provide bronchodilation or directly manage diabetes, making the reduction of hypertension its primary therapeutic use.